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NF-κΒ activator 2 

Cat. No. M29555

All AbMole products are for research use only, cannot be used for human consumption.

NF-κΒ activator 2  Structure
Size Price Availability Quantity
5mg USD 238  USD238 In stock
10mg USD 360  USD360 In stock
25mg USD 565  USD565 In stock
50mg USD 765  USD765 In stock
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Quality Control & Documentation
Biological Activity

NF-κΒ activator 2 is a potent and orally active NF-ҡB activator, with an EC50 of 1.58 μM. NF-κΒ activator 2 induces SOD2 through increasing NF-ҡB expression and activation. NF-κΒ activator 2 can be used for the research of amyotrophic lateral sclerosis (ALS).

Chemical Information
Molecular Weight 298.27
Formula C16H11FN2O3
CAS Number 2375281-44-8
Form Solid
Solubility (25°C) DMSO 250 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Anju Singh, et al. Molecules. Mechanistic Insight into Oxidative Stress-Triggered Signaling Pathways and Type 2 Diabetes

[2] Zeynab Kohandel, et al. Biomed Pharmacother. Anti-inflammatory effects of thymoquinone and its protective effects against several diseases

[3] Daniel S Kikuchi, et al. J Neuroinflammation. Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy

[4] Nasser Hashemi Goradel, et al. J Cell Physiol. Cyclooxygenase-2 in cancer: A review

[5] Keila Lopes Mendes, et al. Cytokine Growth Factor Rev. Nuclear sirtuins and inflammatory signaling pathways

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Keywords: NF-κΒ activator 2  supplier, NF-κB, inhibitors, activators

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