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Neoschaftoside

Cat. No. M18826
Neoschaftoside Structure
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Biological Activity

Neoschaftoside

Chemical Information
CAS Number 61328-41-4
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Gelian Luo, et al. Molecules. UHPLC-Q-Orbitrap-MS-Based Metabolomics Reveals Chemical Variations of Two Types of Rhizomes of Polygonatum sibiricum

[2] Kashif Bashir, et al. J Chromatogr A. Tandem high resolution mass spectrometry based phytochemical composition of Sauromatum guttatum tubers and its enzyme inhibitory potential with molecular docking

[3] Xinfeng Zhang, et al. Food Res Int. Identification and quantitative analysis of phenolic glycosides with antioxidant activity in methanolic extract of Dendrobium catenatum flowers and selection of quality control herb-markers

[4] M Kim, et al. J Chem Ecol. Isolation ofC-glycosylflavones as probing stimulant of planthoppers in rice plant

[5] Chen Xie, et al. Chem Pharm Bull (Tokyo). Flavone C-glycosides from Viola yedoensis MAKINO

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