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MYCi975 (Nuc-0200975) is an orally active MYC inhibitor that disrupts MYC/MAX interactions, promotes MYC T58 phosphorylation and MYC degradation, and impairs myC-driven gene expression. MYCi975 (NUC-0200975) has strong anti-tumor effect and good tolerance, increasing tumor immune cell infiltration and enhancing tumor sensitivity against PD1 immune studies.
| Molecular Weight | 561.3 |
| Formula | C25H16Cl2F6N2O2 |
| CAS Number | 2289691-01-4 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related c-Myc Products |
|---|
| MDEG-541
MDEG-541 is a potent MYC-MAX degrader. |
| c-Myc inhibitor 11
c-Myc inhibitor 11 is a c-MYC inhibitor (pEC50: 6.4). |
| c-Myc inhibitor 12
c-Myc inhibitor 12 is an inhibitor of c-Myc with a pEC50 of 6.4. |
| m-Se3
m-Se3 is a potent and selective c-MYC transcription inhibitor that can inhibit tumor growth and has anti-cancer activity. |
| c-Myc inhibitor 10
c-Myc inhibitor 10, a c-Myc inhibitor, exhibits increased cellular potency, consistent with an increase in permeability with methylation of the morpholine nitrogen. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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