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MW150 (MW01-18-150SRM) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM. MW-150 inhibits the ability of the endogenous p38α MAPK to phosphorylate an endogenous substrate MK2 in activated glia.
| Molecular Weight | 381.47 |
| Formula | C24H23N5 |
| CAS Number | 1628502-91-9 |
| Form | Solid |
| Solubility (25°C) | DMSO 40 mg/mL (ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Fabiana V Campos, et al. Toxins (Basel). Fish Cytolysins in All Their Complexity
[3] Xiaochuan Dai, et al. Nano Lett. Modularized Field-Effect Transistor Biosensors
[4] Miro Kasum, et al. Biochem Med (Zagreb). Macroprolactinemia: new insights in hyperprolactinemia
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