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Mutanolysin

Cat. No. M45212

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Mutanolysin Structure
Size Price Availability Quantity
1KU USD 120  USD120 In stock
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Quality Control & Documentation
Biological Activity

Mutanolysin is an N-acetylcytoplasmic enzyme that cleaves the β-N-acetylcytoplasmic-(1→4)-N-acetylglucosamine bond of the bacterial cell wall polymer peptidoglycan polysaccharide, the carboxyl-terminal portion of which is associated with the recognition of, and binding to, the unique cell wall polymer.Mutanolysin cleaves Listeria monocytogenes and other Gram-positive bacteria (e.g., Lactobacillus spp. and Lactococcus spp.). In addition, Mutanolysin provides gentle cell lysis of readily degradable biomolecules and RNA from bacterial isolates, and can be used to form spheroplasts for DNA isolation.

Chemical Information
CAS Number 55466-22-3
Storage -20℃
References

[1] Donghan Kim, et al. Int J Mol Sci. Mutanolysin-Digested Peptidoglycan of Lactobacillus reuteri Promotes the Inhibition of Porphyromonas gingivalis Lipopolysaccharide-Induced Inflammatory Responses through the Regulation of Signaling Cascades via TLR4 Suppression

[2] K Yokogawa, et al. Antimicrob Agents Chemother. Mutanolysin, bacteriolytic agent for cariogenic Streptococci: partial purification and properties

[3] T Liu, et al. Wei Sheng Wu Xue Bao. [History and prospects of the research on mutanolysin]

[4] J L Siegel, et al. Infect Immun. Mutanolysin-induced spheroplasts of Streptococcus mutants are true protoplasts

[5] M J Janusz, et al. Infect Immun. In vivo degradation of bacterial cell wall by the muralytic enzyme mutanolysin

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Keywords: Mutanolysin supplier, inhibitors, activators

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