Free shipping on all orders over $ 500

mTOR inhibitor-3

Cat. No. M14842

All AbMole products are for research use only, cannot be used for human consumption.

mTOR inhibitor-3 Structure
Size Price Availability
5mg USD 200  USD200 4-7 Days
10mg USD 280  USD280 4-7 Days
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

mTOR inhibitor-3 is a remarkably selective mTOR inhibitor with a Ki of 1.5 nM. mTOR inhibitor-3 suppresses mTORC1 and mTORC2 in cellular and in vivo pharmacokinetic (PK)/pharmacodynamic (PD) experiments.

Chemical Information
Molecular Weight 474.56
CAS Number 1207358-59-5
Solubility (25°C) DMSO 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Shucheng Chen, et al. Autophagy inhibitor potentiates the antitumor efficacy of apatinib in uterine sarcoma by stimulating PI3K/Akt/mTOR pathway

[2] Shaohong Fang, et al. Arsenic trioxide induces macrophage autophagy and atheroprotection by regulating ROS-dependent TFEB nuclear translocation and AKT/mTOR pathway

[3] Dan Li, et al. Sulforaphane Activates a lysosome-dependent transcriptional program to mitigate oxidative stress

[4] Ding-Mei Zhang, et al. TIGAR alleviates ischemia/reperfusion-induced autophagy and ischemic brain injury

[5] Wenyu Zhao, et al. SIRT3 Protects Against Acute Kidney Injury via AMPK/mTOR-Regulated Autophagy

Related mTOR Products
RMC-4627 

RMC-4627 is a selective mTORC1 inhibitor that activates 4EBP1 and inhibits tumor growth.

RMC-4529 

RMC-4529 has an IC50 value of 1.0 nM against p-4E-BP1-(T37/46) in mTOR kinase cellular assay.

WYE-687 dihydrochloride 

WYE-687 dihydrochloride is an ATP-competitive mTOR inhibitor with an IC50 of 7 nM.

Rapamycin-d3

Rapamycin-d3

L-Leucine-d10

L-Leucine-d10

  Catalog
Abmole Inhibitor Catalog




Keywords: mTOR inhibitor-3 supplier, mTOR, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.