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MTK458 is an orally active, brain-permeable PINK1 activator that binds to and stabilizes the active isoform of PINK1, thereby enhancing mitophagy and promoting mitochondrial autophagy (Mitophagy). It can be used in studies related to Parkinson's disease (PD).
| Molecular Weight | 332.32 |
| Formula | C17H15F3N4 |
| CAS Number | 2499962-58-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL |
| Storage | 4°C, dry, sealed |
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