Certificate of Analysis
| Product Name: | MTK458 |
| Catalog Number: | M45064 |
| CAS Number: | 2499962-58-0 |
Physical and Chemical Properties
| Formula: | C17H15F3N4 |
| Molecular Weight: | 332.32 |
| Form: | Solid |
| Solubility: | DMSO 100 mg/mL |
| Storage: | 4°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | MTK458 is an orally active, brain-permeable PINK1 activator that binds to and stabilizes the active isoform of PINK1, thereby enhancing mitophagy and promoting mitochondrial autophagy (Mitophagy). It can be used in studies related to Parkinson's disease (PD). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |