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MS143 is a potent AKT degrader (DC50=46 nM and GI50=0.8 µM in PC3 cells). MS143 induces rapid and robust AKT degradation in a concentration- and time-dependent manner via hijacking the ubiquitin-proteasome system. MS143 can suppress cancer cell growth.
| Molecular Weight | 1121.87 |
| Formula | C59H81ClN12O6S |
| CAS Number | 2376137-41-4 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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Products are for research use only. Not for human use. We do not sell to patients.
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