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MPT0G211 mesylate is a potent, orally active and selective HDAC6 inhibitor (IC50=0.291 nM). MPT0G211 mesylate displays >1000-fold selective for HDAC6 over other HDAC isoforms. MPT0G211 mesylate can penetrate the blood-brain barrier. MPT0G211 mesylate ameliorates tau phosphorylation and cognitive deficits in an Alzheimer’s disease model. MPT0G211 mesylate has anti-metastatic and neuroprotective effects. Anticancer activities.
| Molecular Weight | 389.43 |
| Formula | C18H19N3O5S |
| CAS Number | 2151854-33-8 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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