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ML334 (LH601A) is a nrf2 activator; inhibits Nrf2/Keap1 interaction (Kd = 1 μM). ML334 (LH601A) promotes Nrf2 nuclear translocation and induces antioxidant response element (ARE) activity in vitro. ML334 (LH601A) is cell permeable.
| Molecular Weight | 446.5 |
| Formula | C26H26N2O5 |
| CAS Number | 1432500-66-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 44 mg/mL |
| Storage | 4°C, sealed |
| Related Keap1-Nrf2 Products |
|---|
| CDDO-TFEA
CDDO-TFEA (RTA 404; TP-500) is a trifluoroacetamide derivative of CDDO with enhanced ability to cross the blood-brain barrier. CDDO is an Nrf2 activator that inhibits proliferation and induces differentiation and apoptosis in various cancer cells. CDDO-TFEA can enhance Nrf2 expression and signaling in various neurodegenerative disease models. |
| KI696 isomer
KI696 isomer is the less active isomer of KI696. |
| TAT-14
TAT-14 is a 14-mer peptide that acts as Nrf2 activator with an anti-inflammatory effect. |
| [D-Asp3]-Microcystin-LR
Microcystin-[D-Asp3]-LR/Microcystin A is a cyanotoxin. |
| Keap1-Nrf2 probe
Keap1-Nrf2 probe is a fluorescent Keap1-Nrf2 probe. |
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