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MK8242

Cat. No. M40517

All AbMole products are for research use only, cannot be used for human consumption.

MK8242 Structure

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Quality Control & Documentation
Biological Activity

MK8242 is a small molecule MDM2 inhibitor that stabilizes the tumor suppressor TP53 and can be used in studies related to acute myeloid leukemia and solid tumors.

Chemical Information
Molecular Weight 838.90
Formula C42H48F6N2O7S
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yuan Fang et al. Acta Pharm Sin B. Small-molecule MDM2/X inhibitors and PROTAC degraders for cancer therapy: advances and perspectives

[2] Guochao Liao et al. Eur J Med Chem. The development of piperidinones as potent MDM2-P53 protein-protein interaction inhibitors for cancer therapy

[3] Min H Kang et al. Pediatr Blood Cancer. Initial Testing (Stage 1) of MK-8242-A Novel MDM2 Inhibitor-by the Pediatric Preclinical Testing Program

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  Catalog
Abmole Inhibitor Catalog




Keywords: MK8242 supplier, Mdm2, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
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