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MIV-247 

Cat. No. M28225

All AbMole products are for research use only, cannot be used for human consumption.

MIV-247  Structure

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Quality Control & Documentation
Biological Activity

MIV-247 is a selective cathepsin S inhibitor with Kis of 2.1, 4.2 and 7.5 nM for human, mouse and cynomolgus monkey cathepsin S, respectively.

Chemical Information
Molecular Weight 391.39
Formula C17H24F3N3O4
CAS Number 1352817-76-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Ke Peng, et al. J Cell Physiol. Inhibition of cathepsin S attenuates myocardial ischemia/reperfusion injury by suppressing inflammation and apoptosis

[2] Ellen Hewitt, et al. J Pharmacol Exp Ther. Selective Cathepsin S Inhibition with MIV-247 Attenuates Mechanical Allodynia and Enhances the Antiallodynic Effects of Gabapentin and Pregabalin in a Mouse Model of Neuropathic Pain

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  Catalog
Abmole Inhibitor Catalog




Keywords: MIV-247  supplier, Cathepsin, inhibitors, activators

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