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Milademetan

Cat. No. M13439

All AbMole products are for research use only, cannot be used for human consumption.

Milademetan Structure

Synonym:

DS-3032

Size	Price	Availability	Quantity
1mg	USD 220 USD220	In stock
5mg	USD 550 USD550	In stock
10mg	USD 920 USD920	In stock
25mg	USD 1300 USD1300	In stock
50mg	USD 1750 USD1750	In stock

Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation

Purity: >98.5%
COA
MSDS

Product Information

Biological Activity

Milademetan (DS-3032) is a specific, orally active MDM2 inhibitor for the study of acute myeloid leukemia and solid tumors.

Chemical Information

Molecular Weight	618.53
Formula	C30H34Cl2FN5O4
CAS Number	1398568-47-2
Solubility (25°C)	DMSO : 16.67 mg/mL
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

References

[1] Varsha Ananthapadmanabhan, et al. JCI Insight. Milademetan is a highly potent MDM2 inhibitor in Merkel cell carcinoma

[2] Ying Hong, et al. Clin Transl Sci. Model-based assessments of CYP3A-mediated drug-drug interaction risk of milademetan

[3] Shunji Takahashi, et al. Cancer Sci. Safety and pharmacokinetics of milademetan, a MDM2 inhibitor, in Japanese patients with solid tumors: A phase I study

[4] Jae Heon Jeong, et al. J Clin Med. Elucidation of Novel Therapeutic Targets for Breast Cancer with ESR1-CCDC170 Fusion

[5] Marina Konopleva, et al. Leukemia. MDM2 inhibition: an important step forward in cancer therapy

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Catalog

Abmole Inhibitor Catalog

Keywords: Milademetan, DS-3032 supplier, Mdm2, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.

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