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Methylprednisolone sodium succinate

Cat. No. M25573

All AbMole products are for research use only, cannot be used for human consumption.

Methylprednisolone sodium succinate Structure
Size Price Availability Quantity
10mg USD 50  USD50 In stock
50mg USD 148  USD148 In stock
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Quality Control & Documentation
Biological Activity

Methylprednisolone sodium succinate is a glucocorticoid receptor agonist with immunosuppressive and anti-inflammatory activity that can be converted to active prednisolone in vivo, thereby activating GR-mediated gene expression. In addition, Methylprednisolone sodium succinate can be used to construct a rat model of hormonal femoral head necrosis.

Chemical Information
Molecular Weight 496.5
Formula C26H33NaO8
CAS Number 2375-03-3
Form Solid
Solubility (25°C) Water 50 mg/mL (ultrasonic)
DMSO 25 mg/mL
Storage 4°C, dry, sealed
References

[1] Zhilei Guo, et al. Medicine (Baltimore). Compatibility and stability of methylprednisolone sodium succinate and granisetron hydrochloride in 0.9% sodium chloride solution

[2] Foteini Stefania Koumpa, et al. BMJ Case Rep. Sudden irreversible hearing loss post COVID-19

[3] Chen Peng, et al. Eur J Hosp Pharm. Compatible stability of methylprednisolone sodium succinate and tropisetron in 0.9% sodium chloride injection

[4] Shiqi Cheng, et al. Brain Res Bull. Methylprednisolone sodium succinate reduces BBB disruption and inflammation in a model mouse of intracranial haemorrhage

[5] P L Toutain, et al. J Pharm Sci. Pharmacokinetics of methylprednisolone, methylprednisolone sodium succinate, and methylprednisolone acetate in dogs

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