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Methoxyamine is an orally bioavailable small molecule inhibitor with potential adjuvant activity. Methoxyamine covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER), which may result in an increase in DNA strand breaks and apoptosis.
Nat Commun. 2022 Oct 5;13(1):5868.
Complex genomic patterns of abasic sites in mammalian DNA revealed by a high-resolution SSiNGLe-AP method
Methoxyamine HCl purchased from AbMole
| Molecular Weight | 83.52 |
| Formula | CH6ClNO |
| CAS Number | 593-56-6 |
| Solubility (25°C) | Soluble in Water Soluble in ethanol |
| Storage | 2-8°C, dry, sealed |
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