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Mesembrine ((+)-Mesembrine) a main alkaloid that features an aryloctahydroindole skeleton. Mesembrine is a 5-HT transporter inhibitor with a Ki of 1.4 nM. Mesembrine also inhibits phosphodiesterase 4B (PDE4B) with an IC50 of 7.8 μM.
| Molecular Weight | 289.37 |
| Formula | C17H23NO3 |
| CAS Number | 468-53-1 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[1] Felix Makolo, et al. Phytochemistry. Mesembrine: The archetypal psycho-active Sceletium alkaloid
[3] Lu-Ning Wang, et al. J Org Chem. A Concise Total Synthesis of (-)-Mesembrine
[5] M Shamma, et al. Tetrahedron. The synthesis of (+)-mesembrine
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