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Memoquin 

Cat. No. M30375

All AbMole products are for research use only, cannot be used for human consumption.

Memoquin  Structure

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Quality Control & Documentation
Biological Activity

Memoquin is an anti-amyloid and anti-oxidant multi-target-directed ligand. Memoquin is an orally active inhibitor of BACE-1 and AChE with IC50 values of 108 and 1.55 nM, respectively. Memoquin is a cognitive enhancer that prevents the Aβ-induced neurotoxicity mediated by oxidative stress. Memoquin can be used for the research of Alzheimer’s disease (AD).

Chemical Information
Molecular Weight 632.88
Formula C38H56N4O4
CAS Number 616885-87-1
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Ángel Cores, et al. Antioxidants (Basel). Quinones as Neuroprotective Agents

[2] Valeria Capurro, et al. PLoS One. Pharmacological characterization of memoquin, a multi-target compound for the treatment of Alzheimer's disease

[3] Maria Laura Bolognesi, et al. J Med Chem. Synthesis of monomeric derivatives to probe memoquin's bivalent interactions

[4] M L Bolognesi, et al. Curr Pharm Des. MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond

[5] Maria Laura Bolognesi, et al. Neurotherapeutics. Memoquin: a multi-target-directed ligand as an innovative therapeutic opportunity for Alzheimer's disease

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Keywords: Memoquin  supplier, AChR/AChE, inhibitors, activators

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