Free shipping on all orders over $ 500

Meclofenoxate hydrochloride

Cat. No. M3650
Meclofenoxate hydrochloride Structure
Size Price Availability Quantity
10mM*1mL in DMSO USD 60  USD60 In stock
100mg USD 70  USD70 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Meclofenoxate hydrochloride appears to increase the consolidation of new information into long-term memory. Meclofenoxate does not affect other aspects of remembering. Meclofenoxate is found that significantly more of the subjects receiving meclofenoxate reportes an increased level of mental alertness.

Chemical Information
Molecular Weight 294.17
Formula C12H17Cl2NO3
CAS Number 3685-84-5
Form Solid
Solubility (25°C) DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Marcer D, et al. Age Ageing. The differential effects of meclofenoxate on memory loss in the elderly.

Related AChR/AChE Products
Catestatin

Catestatin is a 21-amino acid residue, cationic and hydrophobic peptide.

α-Conotoxin MII

α-Conotoxin MII (α-CTxMII), a 16-amino acid peptide from the venom of the marine snail Conus magus, potently blocks nicotinic acetylcholine receptors (nAChRs) composed of α3β2 subunits, with an IC50 of 0.5 nM.

COG 133 TFA

COG 133 TFA is a fragment of Apolipoprotein E (APOE) peptide.

α-Bungarotoxin

α-Bungarotoxin is a competitive antagonist at nicotinic acetylcholine receptors (nAChRs).

G-Protein antagonist peptide

G-Protein antagonist peptide is the substance P-related peptide that inhibits binding of G proteins to their receptors.

  Catalog
Abmole Inhibitor Catalog




Keywords: Meclofenoxate hydrochloride supplier, AChR/AChE, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.