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ME0328

Cat. No. M2831

All AbMole products are for research use only, cannot be used for human consumption.

ME0328 Structure
Size Price Availability Quantity
10mM*1mL in DMSO USD 49  USD49 In stock
1mg USD 24  USD24 In stock
5mg USD 46  USD46 In stock
10mg USD 72  USD72 In stock
25mg USD 148  USD148 In stock
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Quality Control & Documentation
Biological Activity

ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.

Chemical Information
Molecular Weight 321.37
Formula C19H19N3O2
CAS Number 1445251-22-8
Solubility (25°C) DMSO 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Xueqian Zuo, et al. Systematic inhibitor selectivity between PARP1 and PARP2 enzymes: Molecular implications for ovarian cancer personalized therapy

[2] Bahram Sharif-Askari, et al. PARP3 inhibitors ME0328 and olaparib potentiate vinorelbine sensitization in breast cancer cell lines

[3] Ming Ji, et al. The Development of a Biotinylated NAD +-Applied Human Poly(ADP-Ribose) Polymerase 3 (PARP3) Enzymatic Assay

[4] Anders E G Lindgren, et al. PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3

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  Catalog
Abmole Inhibitor Catalog




Keywords: ME0328 supplier, PARP, inhibitors, activators

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