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Mavrilimumab (CAM 3001) is a monoclonal antibody that binds to the α subunit of the granulocyte-macrophage colony stimulating factor (GM-CSF) receptor and blocks intracellular signalling downstream of GM-CSF. GM-CSF might be a mediator of the hyperactive inflammatory response associated with respiratory failure and death.
| CAS Number | 1085337-57-0 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[2] Mohamad Amin Pourhoseingholi, et al. Lancet Rheumatol. Mavrilimumab for severe COVID-19
[3] Adil Rashid Khan, et al. Lancet Rheumatol. Mavrilimumab for severe COVID-19
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