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Mavorixafor trihydrochloride (AMD-070 trihydrochloride) is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively.
| Molecular Weight | 458.86 |
| CAS Number | 2309699-17-8 |
| Solubility (25°C) | DMSO 100 mg/mL Water 90 mg/mL |
| Storage | 2-8°C, dry, sealed |
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