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M1002 

Cat. No. M30650

All AbMole products are for research use only, cannot be used for human consumption.

M1002  Structure

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Quality Control & Documentation
Biological Activity

M1002 is a hypoxia-inducible factor-2 (HIF-2) agonist, and can enhance the expression of HIF-2 target genes. M1002 shows synergy with prolyl-hydroxylase domain (PHD) inhibitors.

Chemical Information
Molecular Weight 394.29
Formula C15H8F6N2O2S
CAS Number 823830-85-9
Form Solid
Solubility (25°C) DMSO 50 mg/mL (ultrasonic and warming and heat to 60°C)
DMF 50 mg/mL (ultrasonic)
Storage Powder -20°C
References

[1] Yancheng Yu, et al. Eur J Med Chem. Insight into the binding mode of HIF-2 agonists through molecular dynamic simulations and biological validation

[2] Jonathan Gornall. BMJ. Big cannabis in the UK: is industry support for wider patient access motivated by promises of recreational market worth billions?

[3] Yanqing Miao, et al. Acta Crystallogr Sect E Struct Rep Online. Poly[(μ(5)-3,5-dinitro-benzoato)rubidium]

[4] Bing-Xin Liu, et al. Acta Crystallogr Sect E Struct Rep Online. Bis(2,2'-diamino-4,4'-bi-1,3-thia-zole-κN,N)bis-(nitrato-κO)lead(II) dihydrate

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  Catalog
Abmole Inhibitor Catalog




Keywords: M1002  supplier, HIF, inhibitors, activators

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