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LUNA18

Cat. No. M40562

All AbMole products are for research use only, cannot be used for human consumption.

LUNA18 Structure
Size Price Availability Quantity
1mg USD 1350  USD1350 In stock
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Quality Control & Documentation
Biological Activity

LUNA18 is an orally active RAS cyclic peptide inhibitor that selectively targets, binds and inhibits Ras, thereby inhibiting Ras-dependent signaling and ultimately suppressing the proliferation of Ras-overexpressing tumor cells. It can be used in studies related to solid tumors.

Chemical Information
Molecular Weight 1437.7
Formula C73H105F5N12O12
CAS Number 2676177-63-0
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Atsushi Ohta et al. J Am Chem Soc. Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets

[2] Mikimasa Tanada et al. J Am Chem Soc. Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor

[3] Kenichi Nomura et al. J Med Chem. Broadly Applicable and Comprehensive Synthetic Method for N-Alkyl-Rich Drug-like Cyclic Peptides

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  Catalog
Abmole Inhibitor Catalog




Keywords: LUNA18 supplier, Ras, inhibitors, activators

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