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Lanadelumab

Cat. No. M24667

All AbMole products are for research use only, cannot be used for human consumption.

Lanadelumab Structure
Synonym:

SHP643; DX-2930

Price and Availability

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Quality Control & Documentation
Biological Activity

Lanadelumab (SHP643) is a humanized IgG1 monoclonal antibody against plasma kallikrein (pKal) with an Ki value of 0.12 nM. Lanadelumab inhibits both free and HMWK (high molecular weight kininogen)-bound pKal. Lanadelumab has the potential for the research of hereditary angioedema.

Chemical Information
CAS Number 1426055-14-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] No authors listed. Aust Prescr. Lanadelumab for hereditary angioedema

[2] No authors listed. Lanadelumab

[3] Yahiya Y Syed. Drugs. Lanadelumab: A Review in Hereditary Angioedema

[4] Aleena Banerji, et al. JAMA. Effect of Lanadelumab Compared With Placebo on Prevention of Hereditary Angioedema Attacks: A Randomized Clinical Trial

[5] No authors listed. Lanadelumab

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Keywords: Lanadelumab, SHP643; DX-2930 supplier, Serine/Threonine Protease, inhibitors, activators

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