Certificate of Analysis
| Product Name: | Lanadelumab |
| Catalog Number: | M24667 |
| CAS Number: | 1426055-14-2 |
Physical and Chemical Properties
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Analytical Data
| QC Standard: | |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Lanadelumab (SHP643) is a humanized IgG1 monoclonal antibody against plasma kallikrein (pKal) with an Ki value of 0.12 nM. Lanadelumab inhibits both free and HMWK (high molecular weight kininogen)-bound pKal. Lanadelumab has the potential for the research of hereditary angioedema. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |