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Lampalizumab

Cat. No. M24600

All AbMole products are for research use only, cannot be used for human consumption.

Lampalizumab Structure
Synonym:

RG 7417; TNX 234; Anti-CFD Recombinant Antibody

Price and Availability

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Quality Control & Documentation
Biological Activity

Lampalizumab (RG 7417) is a humanised monoclonal antibody targeting complement Factor D in the alternative complement pathway. Lampalizumab binds an exosite and sterically blocks Factor B access to the active site. Lampalizumab can be used for age-related macular degeneration (AMD) research.

Chemical Information
CAS Number 1278466-20-8
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Katarzyna Samelska, et al. Cent Eur J Immunol. Novel approach to antiangiogenic factors in age-related macular degeneration therapy

[2] María Gil-Martínez, et al. Curr Med Chem. Pharmacological Advances in the Treatment of Age-related Macular Degeneration

[3] Loren S Jack, et al. Dev Ophthalmol. Emixustat and Lampalizumab: Potential Therapeutic Options for Geographic Atrophy

[4] William Rhoades, et al. Clin Ophthalmol. Potential role of lampalizumab for treatment of geographic atrophy

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  Catalog
Abmole Inhibitor Catalog




Keywords: Lampalizumab, RG 7417; TNX 234; Anti-CFD Recombinant Antibody supplier, Complement System, inhibitors, activators

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