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L-Leucine

Cat. No. M10032

All AbMole products are for research use only, cannot be used for human consumption.

L-Leucine Structure
Size Price Availability Quantity
1g USD 20  USD20 In stock
5g USD 25  USD25 In stock
50g USD 60  USD60 In stock
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Quality Control & Documentation
Biological Activity

L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway. Leucine stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing mTORC1 activation. L-Leucine increases intracellular HIF-1α levels and activates the HIF-1α signaling pathway, and these two effects are mediated by the mTOR signaling pathway. This process results in Ngn3 repression and, consequently, decreases β-cell differentiation.

Product Citations
Chemical Information
Molecular Weight 131.17
Formula C6H13NO2
CAS Number 61-90-5
Solubility (25°C) Water 10 mg/mL
Storage 2-8°C, dry, sealed
References

[1] Latif Rachdi, et al. Diabetes. L-leucine alters pancreatic β-cell differentiation and function via the mTor signaling pathway

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Keywords: L-Leucine supplier, mTOR, inhibitors, activators

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