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L-Arabinose

Cat. No. M40516
L-Arabinose Structure
Synonym:

L-(+)-Arabinose

Size Price Availability Quantity
5g USD 50  USD50 In stock
10g USD 70  USD70 In stock
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Quality Control & Documentation
Biological Activity

L-Arabinose is the naturally occurring isomer and is a constituent of plant polysaccharides. Most bacteria contain an inducible arabinose operon that codes for a series of enzymes and transporters that allows L-arabinose to be used as the sole carbon source in microbial culture.

Chemical Information
Molecular Weight 150.13
Formula C5H10O5
CAS Number 5328-37-0
Form Solid
Solubility (25°C) Water 100 mg/mL
Storage RT
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Sarah J Ruddle et al. Cell Host Microbe. Salmonella-liberated dietary L-arabinose promotes expansion in superspreaders

[2] Robert Schleif. EcoSal Plus. A Career's Work, the l-Arabinose Operon: How It Functions and How We Learned It

[3] Erin M Vasicek et al. Front Cell Infect Microbiol. L-Arabinose Transport and Metabolism in Salmonella Influences Biofilm Formation

[4] Toshihisa Kotake et al. J Plant Res. Metabolism of L-arabinose in plants

[5] Bernhard Seiboth et al. Appl Microbiol Biotechnol. Fungal arabinan and L-arabinose metabolism

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