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KT185 

Cat. No. M28514

All AbMole products are for research use only, cannot be used for human consumption.

KT185  Structure

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Quality Control & Documentation
Biological Activity

KT185 is an orally-bioavailable, brain-penetrant and selective ABHD6 inhibitor, with an IC50 0.21 nM in Neuro2A cells.

Chemical Information
Molecular Weight 519.64
Formula C32H33N5O2
CAS Number 1472640-86-0
Form Solid
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Shweta Choudhary, et al. Front Immunol. Identification of SARS-CoV-2 Cell Entry Inhibitors by Drug Repurposing Using in silico Structure-Based Virtual Screening Approach

[2] Ku-Lung Hsu, et al. J Med Chem. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6)

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  Catalog
Abmole Inhibitor Catalog




Keywords: KT185  supplier, MAGL, inhibitors, activators

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