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Dimepiperate

Cat. No. M42494
Dimepiperate Structure
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Quality Control & Documentation
Biological Activity

Dimepiperate (MY 93) is a thiocarbamate (TC) pesticide.

Chemical Information
Molecular Weight 263.4
Formula C15H21NOS
CAS Number 61432-55-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] S C Jung et al. J Nanosci Nanotechnol. Bioavailability of the Nano-Unit 14C-Agrochemicals Under Various Water Potential

[2] Jong Hyouk Park et al. Biomed Chromatogr. Development and validation of a multiresidue method for determination of 37 pesticides in soil using GC-NPD

[3] Yong In Kuk et al. Pest Manag Sci. Cross-resistance pattern and alternative herbicides for Cyperus difformis resistant to sulfonylurea herbicides in Korea

[4] M S Yun et al. Pest Manag Sci. Involvement of cytochrome P-450 enzyme activity in the selectivity and safening action of pyrazosulfuron-ethyl

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