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KDM5-C70 is an ethyl ester derivative of KDM5-C49 and a potent, cell-permeable and pan-KDM5 histone demethylase inhibitor. KDM5-C70 has an antiproliferative effect in myeloma cells, leading to genome-wide elevation of H3K4me3 levels.
Molecular Weight | 336.43 |
Formula | C17H28N4O3 |
CAS Number | 1596348-32-1 |
Form | Oil |
Solubility (25°C) | DMSO 100 mg/mL (ultrasonic) |
Storage | -20°C, sealed |
Related Histone demethylase Products |
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PFI-90
PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action. |
CPI-4203
CPI-4203 is a potent KDM5A inhibitor with an IC50 of 250 nM. |
KDM2B-IN-4
KDM2B-IN-4 is a histone demethylase KDM2B inhibitor. |
Zavondemstat
Zavondemstat (QC8222; TACH 101) is an inhibitor of histone lysine demethylase 4D (KDM4D) with antineoplastic activity. |
Zavondemstat L-lysine
Zavondemstat (QC8222; TACH 101) (L-lysine) is an inhibitor of histone lysine demethylase 4D (KDM4D) with antineoplastic activity. |
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