Certificate of Analysis

 

Product Name: KDM5-C70 
Catalog Number: M28644
CAS Number: 1596348-32-1

Physical and Chemical Properties
Formula: C17H28N4O3
Molecular Weight: 336.43
Form: Oil
Solubility: DMSO 100 mg/mL (ultrasonic)
Storage: -20°C, sealed
Chemical Structure: KDM5-C70  Structure
Analytical Data
QC Standard: ≥98.0%
H-NMR: Consistent with structure
Product Information
Description: KDM5-C70 is an ethyl ester derivative of KDM5-C49 and a potent, cell-permeable and pan-KDM5 histone demethylase inhibitor. KDM5-C70 has an antiproliferative effect in myeloma cells, leading to genome-wide elevation of H3K4me3 levels.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.