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K-975 is a potent, selective and orally active TEAD inhibitor that strongly inhibits protein-protein interactions between YAP1/TAZ and TEAD.
| Molecular Weight | 287.74 |
| Formula | 2563855-03-6 |
| CAS Number | 2563855-03-6 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 200 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related YAP Products |
|---|
| BAY-593
BAY-593 is an orally active GGTase-I inhibitor. |
| SWTX-143
SWTX-143 is a novel covalent YAP/TAZ-TEAD inhibitor that binds to the palmitoylation pocket of all four TEAD isoforms. |
| YAP-TEAD-IN-1
YAP-TEAD-IN-1 is a potent and competitive inhibitor of YAP–TEAD interaction (IC50=25 nM). |
| IAG933
IAG933 is a first-in-class, selective and orally efficacious YAP1/WWTR1(TAZ)-panTEAD protein-protein interaction inhibitor. IAG933 specifically abrogates the interaction between YAP/TAZ coactivators and all four TEAD isoforms, thus selectively inhibiting TEAD-driven transcriptional activity and inducing anti-cancer effects. |
| Lappaol F
Lappaol F, a lignin, is an anticancer agent. |
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