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JZP-MA-11 

Cat. No. M28794

All AbMole products are for research use only, cannot be used for human consumption.

JZP-MA-11  Structure

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Quality Control & Documentation
Biological Activity

JZP-MA-11 is a positron emission tomography (PET) ligand targeting the endocannabinoid α/β-hydrolase domain 6 (ABHD6) enzyme. JZP-MA-11 selectively inhibits ABHD6 with an IC50 value of 126 nM. JZP-MA-11 can cross the blood-brain barrier (BBB). [18F]JZP-MA-11 has the potential for preclinical evaluation targeting the brain ABHD6 in mice and nonhuman primate (NHP).

Chemical Information
Molecular Weight 336.38
Formula C15H17FN4O2S
CAS Number 1672691-50-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Karine Mardon, et al. J Med Chem. Utilizing PET and MALDI Imaging for Discovery of a Targeted Probe for Brain Endocannabinoid α/ β-Hydrolase Domain 6 (ABHD6)

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  Catalog
Abmole Inhibitor Catalog




Keywords: JZP-MA-11  supplier, MAGL, inhibitors, activators

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