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JNJ 10329670

Cat. No. M42301

All AbMole products are for research use only, cannot be used for human consumption.

JNJ 10329670 Structure

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Quality Control & Documentation
Biological Activity

JNJ 10329670 is a potent and selective noncovalent cathepsin S inhibitor with a Ki value of 34 nM for human cathepsin S.

Chemical Information
Molecular Weight 651.14
Formula C30H34ClF3N6O3S
CAS Number 400797-24-2
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Cheryl A Grice et al. Bioorg Med Chem Lett. The SAR of 4-substituted (6,6-bicyclic) piperidine cathepsin S inhibitors

[2] Darin J Gustin et al. Bioorg Med Chem Lett. Discovery and SAR studies of a novel series of noncovalent cathepsin S inhibitors

[3] Robin L Thurmond et al. J Pharmacol Exp Ther. Identification of a potent and selective noncovalent cathepsin S inhibitor

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Keywords: JNJ 10329670 supplier, Cathepsin, inhibitors, activators

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