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IWP 4 is a potent inhibitor of Wnt/β-catenin signaling (IC50 = 25 nM). Has minimal effect on Notch and Hedgehog signaling pathways. Induces differentiation of cardiomyocytes from human ESCs and iPSCs.
| Molecular Weight | 496.62 |
| Formula | C23H20N4O3S3 |
| CAS Number | 686772-17-8 |
| Form | Solid |
| Solubility (25°C) | DMSO 4.97 mg/mL (with sonication) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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