Free shipping on all orders over $ 500

Isopropyl unoprostone

Cat. No. M43879

All AbMole products are for research use only, cannot be used for human consumption.

Isopropyl unoprostone Structure
Synonym:

Unoprostone isopropyl ester; UF-021

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

UF-021, an analog of a prostaglandin metabolite and activator of large conductance calcium-activated potassium channels (BK channels), lowers intraocular pressure (IOP) by increasing aqueous humor outflow, and may be used in studies related to glaucoma.

Chemical Information
Molecular Weight 424.61
Formula C25H44O5
CAS Number 120373-24-2
Form Oil
Storage -20°C
References

[1] Masato Akiyama, et al. Acta Ophthalmol. Therapeutic efficacy of topical unoprostone isopropyl in retinitis pigmentosa

[2] Gui-Lin Zhan, et al. J Glaucoma. Unoprostone isopropyl ester darkens iris color in pigmented rabbits with sympathetic denervation

[3] M Haria, et al. Drugs Aging. Unoprostone (isopropyl unoprostone)

Related Potassium Channel Products
Palmitoyl-L-carnitine chloride

Palmitoyl-L-carnitine chloride (L-Palmitoylcarnitine chloride) is a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. Palmitoyl-L-carnitine chloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2.

VU0810464

VU0810464 is a potent and selective non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator. VU0810464 displays nanomolar potency for neuronal (EC50=165 nM) and GIRK1/4 (EC50=720 nM) channels with improved brain penetration.

QO 58 

QO 58 is a potent modulator of K(v)7 channels.

NS3623 

NS3623 is an activator of human ether-a-go-go-related gene (hERG1/KV11.1) potassium channels.

ML67-33 

ML67-33 is a selective activator of temperature- and mechano-sensitive K2P channels.

  Catalog
Abmole Inhibitor Catalog




Keywords: Isopropyl unoprostone, Unoprostone isopropyl ester; UF-021 supplier, Potassium Channel, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.