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IRE1α kinase-IN-9 is a potent IRE-1α inhibitor, exhibits an average IC50 value of <0.1 μM.
| Molecular Weight | 436.46 |
| Formula | C24H24N2O6 |
| CAS Number | 1338933-30-4 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Diana Pelizzari Raymundo et al. Trends Cancer. Pharmacological Targeting of IRE1 in Cancer
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| STF-083010
STF-083010 is a specific IRE1α inhibitor. STF-083010 inhibits Ire1 endonuclease activity, without affecting its kinase activity, after endoplasmic reticulum stress. STF-083010 is a potent inhibitor of the ER transmembrane protein IRE1, which mediates the unfolded protein response. |
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