Free shipping on all orders over $ 500

Ipafricept

Cat. No. M24643

All AbMole products are for research use only, cannot be used for human consumption.

Ipafricept Structure
Synonym:

OMP-54F28; FZD8-Fc

Price and Availability

For this product's availability, delivery time and price, please email [email protected] directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

Ipafricept (OMP-54F28; FZD8-Fc) is a first-in-class recombinant fusion protein consisting of an extracellular portion of the human frizzled 8 receptor fused to a fragment of human IgG1 Fc that binds Wnt ligand.Ipafricept has solid tumor inhibitory activity and is well tolerated.

Chemical Information
CAS Number 1391727-24-4
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Aastha Jindal, et al. J Clin Exp Hepatol. Hepatocellular Carcinoma: Etiology and Current and Future Drυgs

[2] Masaru Katoh. Int J Mol Med. Multi‑layered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/β‑catenin signaling activation (Review)

[3] Masuko Katoh, et al. Int J Mol Med. Molecular genetics and targeted therapy of WNT-related human diseases (Review)

Related Fusion Proteins Products
Conbercept

Conbercept (KH902) is a monoclonal antibody targeting VEGFRA fused to the IGHG1 Fc fragment. Conbercept is produced by the fusion of the second C-LIKE of FLT1 and the third and fourth C-LIKE of KDR with IGHG1 Fc.

Evorpacept

Evorpacept (ALX148) is a high affinity CD47-blocking fusion protein with an inactive human immunoglobulin Fc region designed to enhance the activity of other anti-neoplastic therapies, with minimal additional toxicity.

Belatacept

Belatacept (BMS 224818) is a fusion protein composed of the Fc fragment of a human IgG1 immunoglobulin linked to the extracellular domain of CTLA-4, which is a molecule crucial in the regulation of T cell costimulation, selectively blocking the process of T-cell activation. Belatacept binds to CD 80/86 ligands and thereby inhibits the CD-28-mediated T-cell costimulation. Belatacept can be used in the research of Immunosuppression in organ transplants.

Baminercept

Baminercept (BG 9924) is a lymphotoxin β receptor IgG fusion protein (LTβR-Ig). Baminercept can be used for the research of many autoimmune diseases including primary Sjögren's syndrome (SS) and rheumatoid arthritis (RA) .

Briobacept

Briobacept (BR 3FC) is a selective human monoclonal antibody targeting to BLyS (BAFF), induces B cells apoptosis. Briobacept is a recombinant glucoprotein, consists of 2 molecules from the BLyS receptor (BR3)and a Fc domain of human IgG1. Briobacept can be used in studies of rheumatoid arthritis (RA).

  Catalog
Abmole Inhibitor Catalog




Keywords: Ipafricept, OMP-54F28; FZD8-Fc supplier, Fusion Proteins, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.