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INH1 is a hec1 inhibitor. Binds Hec1, inhibiting its association with Nek2 and kinetochores. Causes arrest of mitosis and inhibits proliferation in breast cancer cell lines (GI50= 10 - 20 μM).
| Molecular Weight | 344.86 |
| Formula | C18H16N2OS.HCl |
| CAS Number | 313553-47-8 |
| Solubility (25°C) | DMSO 30.84 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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