All AbMole products are for research use only, cannot be used for human consumption.
Indotecan (LMP-400) is a potent topoisomerase 1 (Top1) inhibitor. Indotecan (LMP-400) for P388, HCT116, MCF-7 cell linesIC50 The values are 300, 1200, 560 nM, respectively.
| Molecular Weight | 478.49 |
| Formula | C26H26N2O7 |
| CAS Number | 915303-09-2 |
| Form | Solid |
| Solubility (25°C) | DMSO < 1 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Anish Thomas, et al. Clin Cancer Res. Targeting Topoisomerase I in the Era of Precision Medicine
| Related Topoisomerase Products |
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XR11576 (MLN576) is an orally active inhibitor of topoisomerase I and II. |
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Silatecan (AR-67; DB 67) is a Camptothecin analogue with improved stability and lipophilicity. |
| 9-Hydroxyellipticine hydrochloride
9-Hydroxyellipticine hydrochloride is a inhibitor of Topo II and RyR. |
| Moxifloxacin-d4
Moxifloxacin-d4 |
| F14512
F14512 is a polyamine-containing inhibitor of DNA topoisomerase II with a broad spectrum of antitumor activities. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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