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Imanixil

Cat. No. M30580

All AbMole products are for research use only, cannot be used for human consumption.

Imanixil Structure
Synonym:

HOE-402(free base)

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Quality Control & Documentation
Biological Activity

Imanixil (HOE-402 free base) is an inducer of the LDL receptor (LDLR). Imanixil (HOE-402 free base) is also a potent cholesterol-lowering compound, which inhibits very low density-lipoprotein (VLDL) production, and consequently attenuates atherosclerosis development.

Chemical Information
Molecular Weight 394.35
Formula C17H17F3N6O2
CAS Number 75689-93-9
Form Solid
Solubility (25°C) DMSO 62.5 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Viviane Doggwiler, et al. J Control Release. Efficient colonic drug delivery in domestic pigs employing a tablet formulation with dual control concept

[2] Viviane Doggwiler, et al. Int J Pharm. Tablet formulation with dual control concept for efficient colonic drug delivery

[3] Maria De Mieri, et al. Bioorg Med Chem. Anti-trypanosomal cadinanes synthesized by transannular cyclization of the natural sesquiterpene lactone nobilin

[4] Myriam Sohn, et al. J Biomed Opt. Film thickness frequency distribution of different vehicles determines sunscreen efficacy

[5] Michael Lanz, et al. Drug Dev Ind Pharm. Chewability testing in the development of a chewable tablet for hyperphosphatemia

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Keywords: Imanixil, HOE-402(free base) supplier, inhibitors, activators

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