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Idasanutlin (RG-7388)

Cat. No. M5700

All AbMole products are for research use only, cannot be used for human consumption.

Idasanutlin (RG-7388) Structure
Synonym:

RG-7388

Size Price Availability Quantity
2mg USD 34  USD34 In stock
5mg USD 55  USD55 In stock
10mg USD 95  USD95 In stock
50mg USD 238  USD238 In stock
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Quality Control & Documentation
Biological Activity

Idasanutlin (RG-7388) is a potent and selective p53-MDM2 inhibitor with IC50 of 6 nM showing improved in vitro binding as well as cellular potency/selectivity.

Chemical Information
Molecular Weight 616.48
Formula C31H29Cl2F2N3O4
CAS Number 1229705-06-9
Solubility (25°C) DMSO ≥ 45 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Lehmann C, et al. J Hematol Oncol. Superior anti-tumor activity of the MDM2 antagonist idasanutlin and the Bcl-2 inhibitor venetoclax in p53 wild-type acute myeloid leukemia models.

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Abmole Inhibitor Catalog




Keywords: Idasanutlin (RG-7388), RG-7388 supplier, Mdm2, inhibitors, activators

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