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ICRF-193

Cat. No. M41622

All AbMole products are for research use only, cannot be used for human consumption.

ICRF-193 Structure

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Quality Control & Documentation

Purity:
COA
MSDS

Product Information

Biological Activity

ICRF-193 is an TopoII inhibitor.

Chemical Information

Molecular Weight	282.3
Formula	C12H18N4O4
CAS Number	21416-88-6
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

References

[1] Ashleigh Brindle et al. Inflammation. The Bisdioxopiperazine ICRF-193 Attenuates LPS-induced IL-1β Secretion by Macrophages

[2] Petra Kollárová-Brázdová et al. Clin Sci (Lond). Prodrug of ICRF-193 provides promising protective effects against chronic anthracycline cardiotoxicity in a rabbit model in vivo

[3] Hana Bavlovič Piskáčková et al. Sci Rep. Development of water-soluble prodrugs of the bisdioxopiperazine topoisomerase IIβ inhibitor ICRF-193 as potential cardioprotective agents against anthracycline cardiotoxicity

[4] Norihiko Nakazawa et al. Genes Cells. ICRF-193, an anticancer topoisomerase II inhibitor, induces arched telophase spindles that snap, leading to a ploidy increase in fission yeast

[5] C Tanimoto et al. Acta Med Okayama. ICRF-193 modifies etoposide-induced apoptosis in thymocytes

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Catalog

Abmole Inhibitor Catalog

Keywords: ICRF-193 supplier, Topoisomerase, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.

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