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Icariin is a flavonol glycoside. Icariin inhibited PDE5 and PDE4 activity with IC50 of 432 nM and 73.50 μM, respectively. Icariin is also a PPARα activator. Icariin can increase cardiovascular and cerebrovascular blood flow, promote hematopoiesis, immunity and bone metabolism.
| Molecular Weight | 676.66 |
| Formula | C33H40O15 |
| CAS Number | 489-32-7 |
| Solubility (25°C) | DMSO 70 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] Chunyang He, et al. Pharmacological effects of icariin
[5] Z Wang, et al. The effect of icariin on bone metabolism and its potential clinical application
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