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I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC50=2.7 μM). I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes. I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST.
| Molecular Weight | 310.37 |
| Formula | C17H14N2O2S |
| CAS Number | 459420-09-8 |
| Form | Solid |
| Solubility (25°C) | DMSO 125 mg/mL (ultrasonic) |
| Storage | Powder -20°C |
| Related Hippo (MST) Products |
|---|
| IHMT-MST1-58
IHMT-MST1-58 is an orally active, potent and selective inhibitor of STE20-like protein 1 kinase (MST1) with an IC50 value of 23 nM.It can be used in studies related to type 1 or type 2 diabetes. |
| EMT inhibitor-1
EMT inhibitor-1 is an inhibitor of of Hippo, TGF-β, and Wnt signaling pathways with antitumor activities. |
| XMU-MP-1
XMU-MP-1 is a potent and selective Hippo/ MST1/2 inhibitor with IC50 values of 71.1 ± 12.9 nM and 38.1 ± 6.9 nM, respectively. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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