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Hippo (MST) Hippo/Salvador/Warts

Cat.No.  Name Information
M30114 I3MT-3 I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC50=2.7 μM). I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes. I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST.
M14926 EMT inhibitor-1 EMT inhibitor-1 is an inhibitor of of Hippo, TGF-β, and Wnt signaling pathways with antitumor activities.
M9057 XMU-MP-1 XMU-MP-1 is a potent and selective Hippo/ MST1/2 inhibitor with IC50 values of 71.1 ± 12.9 nM and 38.1 ± 6.9 nM, respectively.
M45321 IHMT-MST1-58 IHMT-MST1-58 is an orally active, potent and selective inhibitor of STE20-like protein 1 kinase (MST1) with an IC50 value of 23 nM.It can be used in studies related to type 1 or type 2 diabetes.




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