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IHMT-MST1-58 is an orally active, potent and selective inhibitor of STE20-like protein 1 kinase (MST1) with an IC50 value of 23 nM.It can be used in studies related to type 1 or type 2 diabetes.
| Molecular Weight | 438.50 |
| Formula | C21H22N6O3S |
| CAS Number | 2414484-25-4 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Hippo (MST) Products |
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I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC50=2.7 μM). I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes. I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST. |
| EMT inhibitor-1
EMT inhibitor-1 is an inhibitor of of Hippo, TGF-β, and Wnt signaling pathways with antitumor activities. |
| XMU-MP-1
XMU-MP-1 is a potent and selective Hippo/ MST1/2 inhibitor with IC50 values of 71.1 ± 12.9 nM and 38.1 ± 6.9 nM, respectively. |
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