Certificate of Analysis

 

Product Name: I3MT-3
Catalog Number: M30114
CAS Number: 459420-09-8

Physical and Chemical Properties
Formula: C17H14N2O2S
Molecular Weight: 310.37
Form: Solid
Solubility: DMSO 125 mg/mL (ultrasonic)
Storage: Powder -20°C
Chemical Structure: I3MT-3 Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC50=2.7 μM). I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes. I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.